Webthese biothiols within single cells still remain challenges, due to their low content (i.e. μM-mM in WebFeb 17, 2015 · Simultaneous discriminative sensing of biothiols in vitro and in living cells has remained challenging. Herein, we report a new sulfonamide-based self-quenched fluorescent probe 1 for this purpose with high sensitivity and good selectivity. Treatment of 1 with cysteine (Cys), homocysteine (Hcy), or glutathione (GSH) yields aminoluciferin, 2 …
Recent Progress in BODIPY-based Fluorescent Probes for Biothiols ...
WebMar 31, 2024 · Developing probes to simultaneously detect and discriminate biothiols is important, yet challenging. Activatable photoacoustic (PA) probes for discriminating … WebMar 1, 2024 · 1. Introduction. Biothiols are a class of essential reducing substances for sustaining micro-environmental redox balance, reducing radical and toxic effect [[1], [2], [3]].Glutathione (GSH), Cysteine (Cys), Hcy (Homocysteine), as most common biothiol molecules, closely regulates psychological and pathological process in human biosystem … iowa fireworks code
High-efficiency dynamic sensing of biothiols in cancer cells with a
WebNov 1, 2024 · A simple and portable photothermal method for biothiols was designed. • The polydopamine nanoparticles with photothermal effects were formed on the surface of ZIF-67. • Biothiols could “weaken” the photothermal signal through decomposition of ZIF-67. • The proposed sensor possessed high sensitivity and specificity for biothiols. • WebMay 25, 2024 · A simple and sensitive electrogenerated chemiluminescence (ECL) sensor array was developed for the discrimination of three biothiols, including homocysteine (Hcy), cysteine (Cys) and glutathione (GSH) using two bis-cyclometalated Ir(III) complexes as ECL probes. Two aldehyde groups bearing bis-cyclometalated Ir(III) complexes were selected … WebNov 3, 2016 · The optical response of Probe 1 for biothiols was investigated in HEPES buffer (10.0 mM, pH 7.4) with 30% CH 3 CN. As shown in Fig. 2, Probe 1 featured an absorption band with a maximum at 498 nm and was almost non-fluorescent. The addition of excessive Cys to the solution of Probe 1 resulted in a 26 nm blue-shift from 498 nm to … opay twitter