WebMethods and analysis AKATSUKI is an open-label, non-randomised, interventional, multicentre study. Twenty participants with congenital HA with FVIII inhibitors will be enrolled from 17 sites across Japan. Emicizumab will be administered subcutaneously, with an initial loading dose of 3 mg/kg once per week (QW) for the first 4 weeks, followed by a … WebSep 23, 2024 · The following treatment approaches will be evaluated: Group 1 - ITI with Nuwiq ®, octanate ® or wilate ® and aPCC/rFVIIa if needed to treat bleeding episodes …
Emicizumab in tolerized patients with hemophilia A with …
WebEmicizumab PUPs and Nuwiq ITI Study. Latest version (submitted February 21, 2024) on ClinicalTrials.gov. A study version is represented by a row in the table. Select two study versions to compare. One each from columns A and B. ... The yellow A/B choices in the table indicate the study versions currently compared below. WebSign up for an account to save the trials you’re interested in following. You can use one account across both BMS Science and Bolder Science to track clinical ... bungay high school bus
Emicizumab PUPs and Nuwiq ITI Study - AdisInsight
WebTo investigate the safety, immunogenicity and hemostatic efficacy of prophylactic Emicizumab given with a concomitant low dose rFVIII (Nuwiq) in Severe WebHOHOEMI (JapicCTI-173710) is a study initiated in Japan, aiming to examine emicizumab prophylaxis in 13 children (<12 years old) including PUPs without inhibitors to FVIII. 36 Emicizumab has been administered at doses of either 3 mg/kg bi-weekly or 6 mg/kg tetra-weekly. In the interim data, 3 out of 6 participants in biweekly cohort and 5 out ... WebFeb 23, 2024 · This study prospectively investigates the safety, FVIII immunogenicity, and hemostaticefficacy of prophylactic HEMLIBRA® given with a concomitant low dose … bungay high school holiday dates