WebApr 12, 2024 · Hydrocyclones are widely used in the separation of two-phase immiscible mixtures. In various application scenarios, three-phase hydrocyclones (3PH) are often urgently needed. In this work, the typical 3PHs are classified into six categories according to their structural characteristics. A comprehensive analysis of their structural feature ... WebDec 17, 2024 · Phase separation promotes cell fate transitions, whereas disruption of phase attenuates the transitions. The major challenge is how to effectively predict mutation residues. For complete details on the use and execution of this protocol, please refer to Wang et al. (2024). Graphical abstract Download : Download high-res image (225KB)
New insight into the significance of KLF4 PARylation in …
WebHere we investigate the role of DNA in nucleation of condensates, using the pioneer transcription factor KLF-4. We show that KLF-4 forms liquid-like condensates on the DNA … WebSep 23, 2024 · The study (“ Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization ”), published in Nature Communications, shows that the binding of KLF4 can... fhgp63cb
Quantifying the phase separation property of chromatin …
WebApr 10, 2024 · Liquid‒liquid phase separation (LLPS) facilitates the formation of membraneless biomolecular condensates, which are crucial for many cellular processes in plants, including embryogenesis, the floral transition, photosynthesis, pathogen defense, and stress responses. The main component required for LLPS is a protein harboring key ... WebJan 14, 2024 · Phase separation describes the large-scale, three-dimensional concentration of proteins and nucleic acids ( Box 1) and is a means by which transcriptional machinery and multiple regulatory elements are brought together. WebAug 28, 2013 · KLF4, as a member of KLF family, expresses in a wide range of tissues in mammals, and plays a critical role in regulating a diverse array of cellular processes … fhgp71al